PMC

(A) Average image-evoked response for excitatory (left panel) and VIP inhibitory cells (right panel) for image presentations where mice were running (mean running speed during the [−0.5, 0.75] second window around stimulus onset was greater than 5 cm/s). Mean image response during running was computed across all running image presentations for each cell, then averaged across cells. Traces show mean ± SEM across cells. (B) Averaged image-locked running speed for image presentations where mice were stationary (mean running speed during the [−0.5, 0.75] second window around stimulus onset was less than 5 cm/s). (C) Average stimulus-triggered running speed across image sets during image presentations where mice were running. Mean running speed was first calculated across all running image presentations within one session, then averaged across sessions. Traces show mean ± SEM across sessions. (D) Average stimulus-triggered running speed across image sets during image presentations where mice were stationary. (E) Average image-locked pupil area during image presentations where mice were running. Mean pupil area was first calculated across all running image presentations within a session, then averaged across sessions. Traces show mean ± SEM across sessions. (F) Average image-locked pupil area during image presentations where mice were stationary.

Deep colors (black, blue, and red) and thin colors (grey, light blue, and pink) are normoxia and hypoxia, respectively. Solid and dotted bars are walking and running, respectively. WN, RN, WH, and RH mean walking at normoxia, running at normoxia, walking at hypoxia, and running at hypoxia, respectively. * walk > running within normoxia or hypoxia and † normoxia < hypoxia within walking or running, respectively. Data are mean ± S.D.

Deep colors (black, blue, and red) and thin colors (grey, light blue, and pink) are normoxia and hypoxia, respectively. Solid and dotted bars are walking and running, respectively. WN, RN, WH, and RH mean walking at normoxia, running at normoxia, walking at hypoxia, and running at hypoxia, respectively. * walking > running within normoxia or hypoxia, § walking < running within normoxia or hypoxia, and † normoxia > hypoxia within walking or running, respectively. Data are mean ± S.D.

(A) Average omission-triggered activity for excitatory (left panel) and VIP inhibitory cells (right panel) for omission trials where mice were running (mean running speed during the ± 2 s window around the omission time was greater than 5 cm/s). Traces show mean ± SEM across cells. (B) Averaged omission-triggered running speed for stimulus omissions where mice were stationary (mean running speed during the omission window was less than 5 cm/s). (C) Average omission triggered running speed across stimulus omissions where mice were running. Mean running speed was calculated for each session, then averaged across sessions. Traces show mean ± SEM across sessions. (D) Average omission-triggered running speed during stimulus omissions where mice were stationary. (E) Average omission-locked pupil area during stimulus omissions where mice were running. Mean pupil area was first calculated for each session, then averaged across sessions. Traces show mean ± SEM across sessions. (F) Average omission locked pupil area during stimulus omissions where mice were stationary.